Communication is the foundation of most multiplayer games, especially highly tactical, cooperative experiences like Monster Hunter. In Tri, if you wanted to talk to the rest of your party, you needed to possess a legendary, rare item known in the the real world as the Wii Speak. Good luck finding someone who bought that thing. Thankfully, those dark days are behind us, because Monster Hunter 3 Ultimate supports voice chat natively, right through the Wii U GamePad. But don't worry if your the type who prefers anonymity, as you'll have access to a full virtual keyboard to tap away at, as well as an option to plug in any USB keyboard via a day-one patch. With all that functionality baked right in, absolutely everyone who plays online will have a voice.
Of course, all of this means nothing if you can't find people to party up with, but that generally doesn't look like it's going to be a problem this time either. Thanks to Friend Codes going the way of the dodo, your Monster Hunter friends list directly integrates with your Wii U one, making it far simpler to friend new players, and invite others to lobbies (though Capcom is still restricting communities by region - so don't expect to play with anyone in Europe or Japan). And remember having to hit message boards to look for people to help you with that pesky 6-star quest? Something tells me that posting on Miiverse will prove a lot more convenient than parsing NeoGAF or GameFAQs.
Further expanding your pool of potential hunting partners is the local cross-platform play with owners of the 3DS version, which allows players to import their characters, items and progress from their Wii U data, and take it on the go to hunt with other Wii U players in person. I got to experience this feature first hand, and was surprised by just how seamless it was. And since the two versions are content identical, everything you earn in one, carries over to the other. Expect this feature to drive sales on both platforms, which means that many more folks to take down a Diablos with.
All told, it looks like Capcom is poised to finally give the Monster Hunter franchise the multiplayer treatment it's always rightfully deserved when it finally releases on March 19th.